Molecular Mechanisms of Human Hypertension
نویسندگان
چکیده
منابع مشابه
Molecular Mechanisms of Human Hypertension
demonstrate that the risk of cardiovascular diseases and death rises in graded fashion with increasing blood pressure (Mosterd et al., 1999; Kannel, 2000). While hy-pertension was once thought to be " essential " for perfu-sion of tissues through sclerotic and narrowed blood and Molecular Biophysics and Biochemistry Yale University School of Medicine vessels, the pathologic nature of elevated b...
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H ypertension has been defined operationally as the level of blood pressure (BP) at which the benefits of treatment exceed the risks.1 It also has been defined in a more concrete way by the Joint National Committee on Hypertension (JNC7) as, in adults, a systolic BP ≥140 mm Hg or a diastolic BP ≥90 mm Hg.2 Hypertension has been shown to be a risk factor for a variety of morbidities, especially ...
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To clarify the pathophysiology of renovascular hypertension, we monitored intraarterial pressure continuously and measured hourly hormone levels for 24 hours under carefully controlled conditions in two hypertensive patients with unilateral renal artery occlusion. Comparison of the results with those obtained when the patients were normotensive 3 months after uninephrectomy indicated that, whil...
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ژورنال
عنوان ژورنال: Cell
سال: 2001
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(01)00241-0